The is an epidemic of obesity and diabetes in the Asia Pacific region. The Pacific Island diet has shifted from one based on traditional root crops and sea food to one relying on energy dense and nutritionally poor imported food.Obesity i.e. BMI greater than 30kg/m2 is found in 30-75 % of different populations in this…
Read moreObesity is a very busy topic.This review in Critical Reviews in Food science and Nutrition makes a thorough evaluation of the 10 putative contributors to the obesity epidemic. The review is comprehensive and well worth readingThe obesity epidemic is a global issue and shows no signs of abating, while the cause of this epidemic remains…
Read moreR Santos et al (2009) .Walking and body mass index in a Portuguese sample of adults: a multilevel analysis. European Journal of Clinical Nutrition 63, 1260–1262; Physical inactivity is an important risk factor for many chronic diseases. This study examined if there were any realtionship between how much individuals walked and body mass index (BMI).…
Read moreHotamisligil has reviewed obesity and its related low grade inflammatory changes. Obesity is associated with chronic low-grade inflammation. Inflammatory signals interfere with insulin action and disrupt metabolic homeostasis. The c-Jun N-terminal kinase (JNK) has been identified as a central mediator of insulin resistance. Recent studies showed that in obesity compromising endoplasmic reticulum (ER) function results…
Read moreIt is a axiom that obesity and lack of activity go together. Ther are three interesting papers in the International Journal of Obesity on this topic. Overall the pointers substantiate the axiom. The first examined the longitudinal relationship between occupational and domestic sources of physical activity and body weight in a sample of Chinese adults.…
Read moreWhere I live in Scotland obesity is a real problem. It is so sad to see young women waddling along with considerable difficulty. What is odd to me is that the old fashioned fat woman was equally fat all over, this new epidemic seems to concentrate the fat around the bottom, and result in a…
Read moreIn any Public Health programme that entails a change in life style it is important that the population at risk should need to recognise that their life style is contributing to real or potential ill health. This applies to alcohol, social behaviour , excessive sized families , smoking and drugs.Alternatively there is the prospect of…
Read moreThis is a review of the variable effect obesity has on insulin and skeletal muscle glucose transport. Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle, insulin resistance can result from high levels of circulating…
Read moreLing Yang1, et al (2008) Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation European Journal of Human Genetics 16, 759–761Herbert et al reported association with obesity of a common DNA variant rs7566605 at 10 kb upstream of the INSIG2 gene. Ling Yang analyzed rs7566605 polymorphism in 3125 Chinese in a…
Read moreGillian Reeves and her colleagues have studied whether there is a relationship between body mass index (kg/m1) and cancer incidence and mortality. They studied a large group of 1.2 million UK women recruited into the Million Women Study, aged 50-64 during 1996-2001, and followed up, on average, for 5.4 years for cancer incidence and 7.0…
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