Mitochondria have important roles in cellular processes, for example, production of cellular energy in the form of ATP and pro¬grammed cell death (apoptosis). Each mitochondrion contains between two and ten copies of mtDNA,. Cells have numerous mitochondria, a cell may harbour several thousand mtDNA copies. Mutations in mtDNA occur at a tenfold or higher rate…
Read moreBariatric surgery, or weight-loss surgery, are the various surgical procedures to treat obe¬sity by modification of the gastrointestinal tract to reduce nutrient intake and/or absorption. This review discusses how appetite and levels of gastrointestinal hormones are altered after bariatric surgery. Surgical removal of.body fat such as liposuction or abdo¬minoplasty are not considered bariatric surgical proce¬dures.…
Read moreWells (2009 ) Thrift: a guide to thrifty genes, thrifty phenotypes and thrifty normsInternational Journal of Obesity (2009) 33, 1331–1338. There is a growing interest in evolutionary models of human adiposity, ‘thrifty genes’ or ‘thrifty phenotypes’, a variety of metabolic or behavioural traits which gives frugality in the expenditure or storage of energy. At the…
Read moreJ Stevens1,2, E G Kat and Huxley (2010) Associations between gender, age and waist circumference European Journal of Clinical Nutrition 64, 6–15;S A Lear et al (2010) Appropriateness of waist circumference and waist-to-hip ratio cutoffs for different ethnic groups European Journal of Clinical Nutrition 64, 42–61;
Read morePeterlik and Cross ( 2009 ) Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology European Journal of Clinical Nutrition vol 63, 1377–1386A compromised vitamin D status, characterized by low 25-hydroxyvitamin D (25-(OH)D) serum levels, and a nutritional calcium deficit are widely encountered in European and North American countries, independent of age or…
Read moreObesity is a very busy topic.This review in Critical Reviews in Food science and Nutrition makes a thorough evaluation of the 10 putative contributors to the obesity epidemic. The review is comprehensive and well worth readingThe obesity epidemic is a global issue and shows no signs of abating, while the cause of this epidemic remains…
Read moreThis is an important paper indicating the molecular biology of cancer of the breast. The amino (N) terminus of BRCA 1 has a RING domain that interacts with ubiquitin-conjugating enzymes and is required for its ubiquitin ligase activity. Ligase enzymes catalyse the joining together ofmolecules of two substances and with a breaking of a diphopsatebond…
Read moreThe role of vitamin D, either alone or in combination with calcium, in reducing fractures in reducing fractures is a contentious issue.. Some studies have shown a reduction in the risk of fractures, others have shown no effect, and one recent study found an increased risk of hip fracture. In the linked study, the DIPART…
Read moreCAMIRE, KUBOW, DONNELLY (2009) Potatoes and Human Health Critical Reviews in Food Sciences and Nutrition vol 49 823-840 The potato (Solanum tuberosum L.) tuber follows only rice and wheat in world importance as a food crop for human consumption. Cultivated potatoes have spread from the Andes of South America where they originated to 160 countries…
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