There is a growing literature on the metabolic effects of excess body fat during childhood. From the available data, it appears that dietary factors are not only important environmental determinants of adiposity, but also may affect components of the metabolic syndrome and modulate the actions of adipokines. Dietary total fat and saturated fat are associated…
Read moreThis is an interesting Review of the Metabolic syndrome: from epidemiology to systems biologyThe Metabolic syndrome is a group of metabolic conditions that occur together and promote the development of cardiovascular disease and diabetes. Recent genome-wide association studies have identified several novel susceptibility genes for Metabolic syndrome traits, and studies in rodent models have provided…
Read moreThis study in Northern Italy in elderly Italians ( 65-91 years old ) showed that physical activity in an elderly Italian protected against the characteristic features of the metabolic syndrome. Physical Activity Scale for the Elderly was inversely correlated with waist circumference, triglyceride and fasting insulin concentration. Any leisure time activity , walking, dancing or…
Read moreIn the Lancet 27th June 2008 the clinical usefulness of the Metabolic Syndrome. is challenged.The metabolic syndrome is a collection of risks for insulin resistance and vascular disease under two principle headingsCardiovascular risk.Global diabetes or cardiovascular risk. Smoking, physical inactivity , unhealthy eating Hypertension Inflammation, hypercoagulation Age, race, sex, family history Abnormal lipid metabolism Overweight…
Read moreThe BMJ has interesting debates on contentious topics and in the 22 March 2008 the question of the value of the diagnosis of the metabolic syndrome is discussed.The International Diabetes Federatioi definition of the metabolic syndrome is Presence of central obesity—Waist circumference varies with ethnicity. If body mass index is >30 central obesity can be…
Read moreSarcopenia that is the loss of muscle mass and strength with age, and is also a feature of type 2 diabetes in the older person .In diabetes there is a relationship between increased glucose concentration and weaker muscle strength.In the Hertfordshire cohort study impaired grip strength runs in parallel with the features of the metabolic…
Read moreSarcopenia that is the loss of muscle mass and strength with age, and is also a feature of type 2 diabetes in the older person .In diabetes there is a relationship between increased glucose concentration and weaker muscle strength.In the Hertfordshire cohort study impaired grip strength runs in parallel with the features of the metabolic…
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