autophagy and starvation

AutophagyAutophagy occurs when cells need to degrade their constituents. This occurs in most normal cells to prevent the accumulation of protein aggregates and defective cellular substructures. During starvation, high temperature, low oxygen, hormonal stimulation or intracellular stress (damaged organelles, accumulation of mutant proteins, microbial invasion) there is activation of signalling pathways that increase autophagy.The enzyme…

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