Control of gene regulation, ? a role for soya

Differential expression of the eukaryotic genome through cell differentiation or response to environmental changes requires specific modulation of its nuclear organization. These processes enable regulated genes to prevail against regulatory constraints of chromatin structure in which DNA is wrapped around core nucleosomes consisting of octamers of histones H2A. H2B, H3 and H4. Overcoming the structural…

Read more

Isoflavones, oestrogen like activity

Isoflavones and their similarity to oestrogens., structurally and functionally Isoflavones are plant chemicals which belong to the family of phyto-oestrogens. There are of interest to nutrition and health due to their potential oestrogenic properties in the body. There is close structural relationship of genistein and daidzein compared with 17ß-oestrodiol. Although oestrogenicity assays have reported low…

Read more
Back to top