genes, disease liability, genome wide association, diabetes

In 1913, RA Fisher, an evolutionary biologist and pioneer of modern statistics, published a paper on the genetic causes of dis­ease that brought together two rival factions.1. Geneticists who proposed a theory that diseases worked like Mendel’s pea plants, with just one or two genes responsible for each condition.2. Biometricians, however, advocated a continuous distribution…

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