Several fines of evidence have suggested extensive proliferaton activity and pluripotency of germline stem cells, including spermatogonial stem cells .
In an early embryo a cell has the potential to generate many different cell types. During development cells generally lose this potential or ’potency’, and become restricted to making one or a few cell types. Cells can become undetermined and undifferentiated in special circumstances. These Undifferentiated cells which are capable of self-renewal and differentiation into more specialised cells are called stem cells . . Stem cells have the potential to develop into many different cell types in the body They might act as a repair system for the body, they can theoretically divide without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential to either remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or » brain cell.
Karin Nayernia ( 2007 : Stem cell derived from testis show promise for treating a wide variety of medical condition’ Cell Research 17, 895-897 )
Has written a review showing the possibility of using the continued presence of stem cells in the testis for the repair of medical problems. The maturation of such stem cells may well have needs for nutritional support in as yet unsuspected ways.
- Martin Eastwood