probiotics and diarrhoea in children

Probiotics are all the rage. But not all act in an effective manner. In a clinical trial of young children aged 3-36 months a variety of five probiotics drinks were compared over five days
The trial was to ask the children’s parents purchase a specific probiotic product: oral rehydration solution (control group); Lactobacillus rhamnosus strain GG;Saccharomyces boulardii; Bacillus clausii; mix of L delbrueckii var bulgaricus, Streptococcus thermophilus,L acidophilus, and Bifidobacterium bifidum; or Entemcoccus faecium SF68.
The outcome of success was judged by duration of diarrhoea and daily number and consistency of stools. Secondary outcomes were duration of vomiting and fever and rate of admission to hospital. Safety and tolerance were also recorded.
The median duration of diarrhoea was significantly shorter (PNot all commercially available probiotics preparations are effective in children with acute diarrhoea.
Canani et al 2007 Probiotics for treatment of acute diarrhoea in children: randomised clinical trail of five diffeent preparations. BMJ 335, 340-2

Martin Eastwood
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