The influence of different types of exercise on risk factors for cardiovascular diseases has rarely been investigated. The aim of a study by Pitsavos et al in the QJM 2009 was to evaluate the effect of adding resistance exercise to aerobic activities on lipid-lipoprotein profile, in a representative sample of men and women from the province of Attica, Greece.
They randomly enrolled 1514 and 1528 healthy men and women, respectively, stratified by city, age and gender distribution. Participants were classified as inactive, sufficiently active and highly active for either aerobic activities alone or a combination of aerobic plus resistance exercise (HAC). The activities usually associated with cardiorespiratory fitness are anaerobic and activities with concentric and eccentric muscle are resistance.
The main outcome measures are lipid-lipoprotein profile [total, high-density lipoprotein (HOL) cholesterol, low-density lipoprotein (LOL) cholesterol, triglycerides, apolipoprotein-A 1, apolipoprotein-B] and anthropometric indices.
From those participating in aerobic activities, 480 (31 .7%) men and 502 (32.9%) women were classified as sufficiently active, 100 men (6.6%) and 93 women (6.1%) as highly active for either aerobic activities and 90 men (5.9%) and 49 women (3.2%) as combination of aerobic plus resistance exercise. After various adjustments were made, men from the combination of aerobic plus resistance exercise group had an average of 23% lower plasma triacylglycerol concentration (p= 0.04) and 10% lower LDL-cholesterol (P= 0.01) when compared with the highly active for either aerobic activities group. Moreover, women from the combination of aerobic plus resistance exercise group had 13% lower LDL-cholesterol when compared with highly active for either aerobic activities group (P= 0.051).
These data suggest that combining aerobic and resistance-type activities may confer a better effect on lipoprotein profile in healthy individuals than aerobic activities alone.
Pitsavos et al 2009 Resistance exercise plus to aerobic activities is associated with better lipid’s profile among healthy individuals : The ATTICA study. QJMed vol 102 pp 609-616

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