Open chromatin and diabetes

Groop (2010 Open chromatin and diabetes risk, ) Nature Genetics 42, 190 – 192 (2010) A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes–associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and…

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