Investigations into the health effects of whole flaxseed or flaxseed products (for example, defatted flaxseed meal, flax¬seed extracts) in human clinical trials and animal models have shown beneficial changes in blood lipid profiles and protection against some types of cancer. However, such studies do not show which flaxseed component(s) the benefits can be attributed, as…
Read moreWhat makes two individuals different.? Less the genome sequence , which has a minor place but the epigenome , a set of chemical modifications, not encoded in DNA , which dictate how and when genes are expressed. There are many ways of epigenetic modification, which includes methylation of the DNA , histones that wind around…
Read moreThis paper describes the effect of fruit and vegetable intake on the chances of developing cancer. The population studied was 500, 000 people or so, aged 25 to 75 from 10 Western European countries. . There is virtually no benefit of 5 fruit and vegetables a day for cancer protection. 200 g of fruit and…
Read moreImmortal time in observational studies can bias the results in favour of the treatment group, but it is not difficult to identify and avoid. Well designed observational studies have made important contributions to our understanding of the risks and benefits of drug treatment. Such studies are often the first to identify or confirm important adverse…
Read moreGroop (2010 Open chromatin and diabetes risk, ) Nature Genetics 42, 190 – 192 (2010) A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes–associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and…
Read moreAtfi and Baron( 2010) PTH battles TGF-β in bone Nature Cell Biology 12, 205 – 207 (2010) Bone remodelling in vertebrates is coordinately regulated by the opposing effects of parathyroid hormone (PTH) and transforming growth factor-beta (TGF-β). PTH couples the processes of bone resorption and formation by enforcing simultaneous internalization of TGF-β type II receptor…
Read moreVujkovic et al ( 2010 ) European Journal of Clinical Nutrition (2010) 64, 266–273; The maternal homocysteine pathway is influenced by riboflavin intake and MTHFR polymorphisms without affecting the risk of orofacial clefts in the offspring Riboflavin is a cofactor for the 5,10-methylenetetrahydrofolate reductase (MTHFR) enzyme involved in the homocysteine pathway. The aim of this…
Read moreBuja et al (2010 ) European Journal of Clinical Nutrition (2010) 64, 297–307; Alcohol consumption and metabolic syndrome in the elderly: results from the Italian longitudinal study on aging Although there is plenty of evidence of the association between metabolic syndrome (MS) and cardiovascular disease, the relationship between alcohol consumption and metabolic syndrome is still…
Read moreWater is essential for lifeDirty contaminated water, which is world wide phenomenon, is a threat to lifeIn many rural communities there is a shortage of water which may be contaminated.The prime problem is bacteria and viruses, but also toxic elements e.g. arsenic.Filtering the dirt and bacteria is the best method. There are several other methods1.…
Read moreOkarter and Liu (2010 ) Health Benefits Phytochemicals of Whole Grain. Critical Reviews in Food Science and Nutrition vol 50, 193-208 A whole grain consists of the intact, ground, cracked, or flaked caryopsis, whose principal anatomical components, the starchy endosperm, germ. and bran-are present in the same relative proportions as they exist in the intact…
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