This leader is very important in the care of marginally encephalopathic patients. Leader 2008 Nature Clinical Practice Gastroenterology & Hepatology 5, 537
Probiotic yogurt can reverse MHE in patients with nonalcoholic cirrhosis
Minimal hepatic encephalopathy (MHE) affects 60–80% of patients with cirrhosis and is associated with poor quality of life, decreased work performance and impaired driving skills. Lactulose has been advocated as the first-line therapy for MHE, but long-term adherence is limited because of adverse gastrointestinal effects. Alternative, long-term therapies are, therefore, needed. Bajaj and colleagues investigated the use of probiotic yogurt for the treatment of MHE in patients with nonalcoholic cirrhosis. Yogurt was chosen because it is a palatable food item that is widely available and does not require prescription, all of which favour long-term adherence.
- Martin Eastwood