HDL cholesterol and cardiovascular risk

Cardiovascular disease is the leading cause of death worldwide. Reducing concentrations of LDL cholesterol with statin therapy has resulted in reductions of 23% in cardiovascular risk for every 1•03 mmol/L (40 mg/dL) decrease in LDL cholesterol. However, despite a reduction in LDL cholesterol with high-dose statins to 1•6 mmol/L in patients with stable coronary heart…

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