Monthly Archives: July 2008

biological cooperativity reviewd

Cooperativity is the basis for a variety of microscopic events, such as the simultaneous chelation of metal ions, the temporal coordination of protein folding and the concerted function of biomolecular assemblies. At the macroscale, cooperation between scientific laboratories, organizations and countries is required to advance research in a timely manner and to coordinate conferences and…

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Newton and Nutrition

One thing that still intrigues Melvyn Bragg in his news letter In Our Time BBC 03-084-2008 is the idea that Newton for example can derive the laws of motion without experimental evidence. In this regard there was a lovely quotation from Descartes speaking of Galileo: “he builds without foundations”. Galileo declared that whatever causes gravity…

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Julie Andrews on growing older

To commemorate her birthday , actress/vocalist, Julie Andrews made a special appearance at Manhattan ‘s Radio City Music Hall for the benefit of the AARP. One of the musical numbers she performed was ‘My Favorite Things’ from the legendary movie ‘Sound Of Music’. Here are the lyrics she used: > > > > > >…

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Alzheimers disease aetiology

Two defining features of Alzheimer’s disease in the brain are amyloid plaques and neurofibrillary tangles (tau). The plaques contain a protein called amyloid-beta, while the tangles are made of a protein called tau. The current, widely accepted amyloid hypothesis regards Alzheimer’s as being due to plaque deposits, whereas the tau hypothesis links the disease to…

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protein degradation mechanism,

The proteasome,The 26S proteasome is one of the principal cellular machines for degrading proteins. Proteins to be destroyed are marked with tags in the form of the small protein ubiquitin, and when the proteasome encounters such polyubiquitinated proteins, it catches, then degrades them. The proteasome has, not one, but at least two hands with which…

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drugs in sport

The use of pharmacologically active drugs to enhance sporting prowess is widespread. The usage has increased over the last 40 yearsThe usage of such drugs is not only cheating but also threatens the long term health of the person so indulging. Sjoqvist and Rane have reviewed the area in Lancet 2008 vol 371 May 31st.…

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metabolic syndrome

In the Lancet 27th June 2008 the clinical usefulness of the Metabolic Syndrome. is challenged.The metabolic syndrome is a collection of risks for insulin resistance and vascular disease under two principle headingsCardiovascular risk.Global diabetes or cardiovascular risk. Smoking, physical inactivity , unhealthy eating Hypertension Inflammation, hypercoagulation Age, race, sex, family history Abnormal lipid metabolism Overweight…

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