genes and cancer of the colon
Genes and the aetiology of colonic cancer.Sansom O J et al 2007, Nature April 5th , vol 446, 676-679The APC gene encodes the adenomatous polyposis coli tumour suppressor protein. Mutation of the germline characterizes familial adenomatous polyposis (FAP), an autosomal intestinal cancer syndrome. Inactivation of APC is also recognized as the key early event in…
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